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The incorporation of flavonoids into pharmacological antihypertensive treatment demonstrates supplementary advantages for blood pressure, lipid profile, leptin levels, obesity, and inflammation (496)

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The more efficient conjugation of the QIs to GSH may have reduced covalent modification of cellular macromolecules, like ER proteins Grp78/Bip (Xu et al., 2015), microsomal GST (Weis et al., 1992), and PDI ( Although reactive QI formation has been associated with AQ-induced (cyto)toxicity in vitro ( in vivo (Wink et al., 2014, 2017)

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